Andrew McArthur, PhD

Andrew McArthur, PhD

 mcarthur-01

Associate Professor
Department of Biochemistry and Biomedical SciencesCisco Research Chair in Bioinformatics

MDCL 2322
McMaster University
905-525-9140 ext. 21663
mcarthua@mcmaster.ca

Research

  • Biological database design and predictive analytics, particularly in the areas of antimicrobial drug resistance and molecular epidemiology
  • Comprehensive Antibiotic Resistance Database (arpcard.mcmaster.ca)
  • Development of Integrated Health Biosystems research at McMaster University, bridging data-intensive biomedical research and clinical healthcare
  • Bioinformatics workflows and Cloud computing for gene expression, gene regulation, and population genomics
  • Next generation DNA sequence analysis, genome assembly, and genome annotation
  • Molecular phylogenetics and phylogenomics
  • Ecotoxicogenomics of environmental contaminants (metals, organics, pharmaceuticals) using zebrafish, mouse, and other model systems.

The McArthur laboratory’s research program is rooted in bioinformatics, functional genomics, and computational biology. It spans complex informatics approaches to the functional genomics of microbial drug resistance, development of biological databases, next generation sequencing for genome assembly and molecular epidemiology, automated literature curation approaches, controlled vocabularies for biological knowledge integration, and functional genomics approaches in environmental toxicology. As part of our Cisco funded program, we additionally research the use and generation of ‘Big Data’ in the biomedical sciences, with the goal of integrating biomedical research and clinical healthcare.